Having large feet myself, I'm of the opinion that:
- you can never have too big an enclosure. 1590Bs are for wusses
- IDK how big your pcb/vero is but if you can stagger the footswitches (maybe in a V shape?), that's good enough. I'd mount all the pots on the top (north), once the pedal is on the floor I almost never fiddle with pots anymore. You can naturally put them on left/right (east/west) sides to be protected by guitar cable but that's just too unsightly to me...
Honestly, I'd just get a bigger box. I normally box three-footswitch stuff inside 1790NS.