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I learned the hard way about crosstalk. One of my very first builds was a Fuzz Factory in a 1590B. After testing the built up circuit out of the box, which worked perfectly, I crammed all the pots and wires into the enclosure, and fired it up. WHIIIIIIINE!. So I took it all out again, tested again - worked perfectly, put it all back in, and got the same result.
I ended up repeating this a total of SIX TIMES, before I twigged what was going on. After carefully separating my signal and power wires, I finally got it working without whining and squealing all the time.
Now I always make sure I have good separation, my board input an output wires go down one side of the box, and I use two core plus ground shielded wire to run from the footswitch to the jacks. This sits on top of the board input and output wire.
On the opposite side of the enclosure, I have my power socket, LED, and the battery snap, and all the battery, power socket and indicator LED wires run down this side.
If a power line needs to cross or pass next to a signal line, try to make sure that they cross each other at 90 degrees, rather than have them run alongside each other. Running your power lines around the very edge of your enclosure also helps a lot, as it keeps them as close to ground as possible.
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